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. 2002 Aug;25(8):563-6.

[Effect of traditional Chinese medicine compounds Aining on the expression of apoptosis inducing genes of human gastric cancer cell]

[Article in Chinese]
Miancheng Su  1 , Mei Dai, Xiaoying Lü, Hongkun Li, Jilin Liu
Affiliations
  • PMID: 12599692

[Effect of traditional Chinese medicine compounds Aining on the expression of apoptosis inducing genes of human gastric cancer cell]

[Article in Chinese]
Miancheng Su et al. Zhong Yao Cai. 2002 Aug.

Abstract

Objective: To investigate the effects of Aining on the genes of the human gastric cancer cells.

Methods: Flow cytometry(FMC) was adopted to detect the gene expression of the gastric cancer cell in the Aining group, the cisplatin(DDP) group and the blank group.

Results: Compared with the blank group, the expression of c-myc and bcl-2 genes was low, while that of the p53, bax genes was high(P < 0.01), and the ratio of bax/bcl-2 significantly increased in both the Aining group and the cisplatin(DDP) group.

Conclusions: The mechanism of inducing the human gastric cancer cells apoptosis by Aining has some relationship with the changes of the genes.

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