Review
doi: 10.1016/s0092-8674(03)00118-1.
Membrane domains in the secretory and endocytic pathways
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- PMID: 12600314
- DOI: 10.1016/s0092-8674(03)00118-1
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Review
Membrane domains in the secretory and endocytic pathways
Cell.
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Abstract
Progress in identifying, characterizing, and localizing the constituents of distinct membrane bound compartments has revealed a new level of intracellular subcompartmentation. Proteins and lipids are not uniformly distributed in a given organelle, and subdomains are formed by a combination of hierarchical assembly processes and protein exclusion. Thus, functionally distinct specializations of a given organelle are physically segregated to a greater extent than previously believed.
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