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Review
. 2003 Mar;9(1):93-109.
doi: 10.1023/a:1021886207236.

A model of aging and a shape of the observed force of mortality

M S Finkelstein  1
Affiliations
Review

A model of aging and a shape of the observed force of mortality

M S Finkelstein. Lifetime Data Anal. 2003 Mar.

Abstract

A probabilistic model of aging is considered. It is based on the assumption that a random resource, a stochastic process of aging (wear) and the corresponding anti-aging process are embedded at birth. A death occurs when the accumulated wear exceeds the initial random resource. It is assumed that the anti-aging process decreases wear in each increment. The impact of environment (lifestyle) is also taken into account. The corresponding relations for the observed and the conditional hazard rate (force of mortality) are obtained. Similar to some demographic models, the deceleration of mortality phenomenon is explained via the concept of frailty. Simple examples are considered.

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References

    1. J R Stat Soc Ser A Stat Soc. 1999;162(Pt. 1):5-43 - PubMed
    1. Science. 1992 Oct 16;258(5081):457-61 - PubMed
    1. J Mol Biol. 1992 Jun 20;225(4):951-60 - PubMed
    1. Demography. 1979 Aug;16(3):439-54 - PubMed

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