Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Multicenter Study
. 2003 Feb 15;31(2):93-7.
doi: 10.1016/s0212-6567(03)79144-6.

[Is the breath test reliable in primary care diagnosis of Helicobacter pylori infection?]

[Article in Spanish]
J Valdepérez  1 , R Vicente, M P Novella, L Valle, B Sicilia, C Yus, F Gomollón
Affiliations
Multicenter Study

[Is the breath test reliable in primary care diagnosis of Helicobacter pylori infection?]

[Article in Spanish]
J Valdepérez et al. Aten Primaria. .

Abstract
in English, Spanish

Objective: To evaluate the reliability of the breath test urea 13C in the primary care for the diagnosis of Helicobacter pylori (Hp) infection.

Design: Descriptive, prospective and multicentric.Location. Urban area belonging to the Health Center Actur Sur of Zaragoza with participation of Miguel Servet Hospital.

Participants: 87 patients with clinical diagnosis of functional dispepsia. In all of them was made a breath test with 13C urea as well as a gastroscopy with taking of samples for histology and ureasa fast test.

Main measurements: Age, sex and the presence of positivity or negativity of infection by Hp were valued in the histology, ureasa test and in the breath test, considering the histology and the ureasa test like gold tests for this measurement, reason why it was demanded that the positive or outside negative result in both considering it nonambiguous.

Results: Two cases were excluded by ambiguous results. The 77.6% (66/85) were positive by histology and ureasa test, and these, 92.4% (61/66) were positives to the breath test. The sensitivity of this test was 92% and the specificity 100%.

Conclusions: The breath test in primary care has a high value diagnosis of Hp infection, being able to avoid, in some cases, another invasives techniques like gastroscopy.

Objetivo: Evaluar la fiabilidad del test del aliento con urea 13C en atención primaria para el diagnóstico de infección por Helicobacter pylori (Hp).

Diseño: Estudio descriptivo, prospectivo y multicéntrico.

Emplazamiento: Área urbana perteneciente al Centro de Salud Actur Sur de Zaragoza, con participación del Hospital Miguel Servet.

Participantes: Se incluyó a 87 pacientes con diagnóstico clínico de dispepsia funcional. A todos ellos se les realizó un test de aliento con urea 13C, así como una gastroscopia con toma de muestras para histología y test de ureasa rápida.

Mediciones principales: Se valoraron edad, sexo y la presencia de positividad o negatividad de infección por Hp en la histología, el test de ureasa y el test del aliento, considerando la histología y el test de ureasa pruebas gold standard para esta medición, por lo que se exigía que el resultado en ambas fuera positivo o negativo para considerarlo no equívoco.

Resultados: Se excluyeron 2 casos por resultados equívocos. El 77,6% (66/85) fue positivo por histología y test de ureasa, de los que un 92,4% (61/66) resultó positivo al test del aliento. La sensibilidad de esta prueba fue del 92% y la especificidad del 100%.

Conclusiones: El test del aliento en atención primaria tiene un alto valor diagnóstico de infección por Hp, pudiendo evitar así en algunos casos la realización de técnicas más invasivas como la gastroscopia.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

    1. Bytzer P. Diagnosing dyspepsia: any controversies left? Gastroenterology. 1996;110:302–306. - PubMed
    1. Talley N.J., Stanghellini V., Heading R.C., Koch K.L., Malagelada J.R., Tytgat G.N.J. Functional gastroduodenal disorders. Gut. 1999;45(Suppl II):37–42. - PMC - PubMed
    1. Kray E. Nonulcer dyspepsia introduction: epidemiological data. Scand J Gastroenterol. 1982;17:6–8. - PubMed
    1. Tibblin G. Introduction to the epidemiology of dyspepsia. Scand J Gastroenterol. 1985;20(Suppl 109):29–33. - PubMed
    1. Penston J.G., Pounder R.E. A survey of dyspepsia in Great Britain. Aliment Pharmacol Ther. 1996;10:83–89. - PubMed

Publication types