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. 2003 Mar 1;19(4):524-31.
doi: 10.1093/bioinformatics/btg015.

The systems biology markup language (SBML): a medium for representation and exchange of biochemical network models

M Hucka  1 , A Finney, H M Sauro, H Bolouri, J C Doyle, H Kitano, A P Arkin, B J Bornstein, D Bray, A Cornish-Bowden, A A Cuellar, S Dronov, E D Gilles, M Ginkel, V Gor, I I Goryanin, W J Hedley, T C Hodgman, J-H Hofmeyr, P J Hunter, N S Juty, J L Kasberger, A Kremling, U Kummer, N Le Novère, L M Loew, D Lucio, P Mendes, E Minch, E D Mjolsness, Y Nakayama, M R Nelson, P F Nielsen, T Sakurada, J C Schaff, B E Shapiro, T S Shimizu, H D Spence, J Stelling, K Takahashi, M Tomita, J Wagner, J Wang; SBML Forum
Affiliations

The systems biology markup language (SBML): a medium for representation and exchange of biochemical network models

M Hucka et al. Bioinformatics. .

Abstract

Motivation: Molecular biotechnology now makes it possible to build elaborate systems models, but the systems biology community needs information standards if models are to be shared, evaluated and developed cooperatively.

Results: We summarize the Systems Biology Markup Language (SBML) Level 1, a free, open, XML-based format for representing biochemical reaction networks. SBML is a software-independent language for describing models common to research in many areas of computational biology, including cell signaling pathways, metabolic pathways, gene regulation, and others.

Availability: The specification of SBML Level 1 is freely available from http://www.sbml.org/

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