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Review
. 2003 Jan;57(1-2):61-87.
doi: 10.1016/s0166-3542(02)00201-2.

Molecular diagnostics of viral hemorrhagic fevers

Christian Drosten  1 , Beate M Kümmerer, Herbert Schmitz, Stephan Günther
Affiliations
Review

Molecular diagnostics of viral hemorrhagic fevers

Christian Drosten et al. Antiviral Res. 2003 Jan.

Abstract

This review addresses the diagnostics of viral hemorrhagic fevers (VHFs). In the first part, an overview is given on classical methods of VHF diagnostics as well as novel molecular diagnostic tools. Currently available polymerase chain reaction (PCR) assays for diagnosis of VHF are summarized and discussed. In the second part, VHF diagnostics are described in particular for Lassa fever, yellow fever, and Crimean-Congo hemorrhagic fever, based on cases that were imported into or occurred within Europe. The third part is focussed on important differential diagnoses of VHF.

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