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. 1976 Mar;4(4):257-61.
doi: 10.1016/0303-7207(76)90059-9.

Immunohistochemical localization of somatostatin in endocrine cells of the rat stomach

R Leclerc, G Pelletier, R Puviani, A Arimura, A V Schally

Immunohistochemical localization of somatostatin in endocrine cells of the rat stomach

R Leclerc et al. Mol Cell Endocrinol. 1976 Mar.

Abstract

Using an immunohistochemical technique involving unlabeled antibody and the peroxidase-anti-peroxidase complex, we have localized somatostatin (or growth hormone-release inhibiting hormone), a hypothalamic hormone which can also inhibit gastrin secretion, in the rat stomach. Somatostatin was found to be present in a few cells in the mucosa of the pyloric antrum. These cells are characterized by the presence of secretory granules of about 150-250 nm in diameter and are probably endocrine cells.

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