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. 2003 Mar 7;299(5612):1582-5.
doi: 10.1126/science.1080857.

Traces of human migrations in Helicobacter pylori populations

Daniel Falush  1 , Thierry Wirth, Bodo Linz, Jonathan K Pritchard, Matthew Stephens, Mark Kidd, Martin J Blaser, David Y Graham, Sylvie Vacher, Guillermo I Perez-Perez, Yoshio Yamaoka, Francis Mégraud, Kristina Otto, Ulrike Reichard, Elena Katzowitsch, Xiaoyan Wang, Mark Achtman, Sebastian Suerbaum
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Traces of human migrations in Helicobacter pylori populations

Daniel Falush et al. Science. .

Abstract

Helicobacter pylori, a chronic gastric pathogen of human beings, can be divided into seven populations and subpopulations with distinct geographical distributions. These modern populations derive their gene pools from ancestral populations that arose in Africa, Central Asia, and East Asia. Subsequent spread can be attributed to human migratory fluxes such as the prehistoric colonization of Polynesia and the Americas, the neolithic introduction of farming to Europe, the Bantu expansion within Africa, and the slave trade.

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