Overview of cortical plasticity and recovery from brain injury

Abstract

The analysis of plastic changes in the nervous system is based on the assumption that the nervous system is not a static system but rather one that changes over time. Neural plasticity can be studied at many levels, beginning with behavior and then becoming progressively more microscopic by descending to the level of cerebral maps, synaptic organization, physiologic activities, molecular structure, and mitosis. This article considers each level in turn and then briefly describes how an understanding of the principles of plasticity can be used to initiate treatments for cerebral injury.