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. 1976 May 1;143(5):1277-82.
doi: 10.1084/jem.143.5.1277.

The HLA system in the families of patients with juvenile diabetes mellitus

P Rubinstein, N Suciu-Foca, J F Nicholson, M Fotino, A Molinaro, L Harisiadis, M A Hardy, K Reemtsma, F H Allen Jr

The HLA system in the families of patients with juvenile diabetes mellitus

P Rubinstein et al. J Exp Med. .

Abstract

The HLA and Bf genotypes were determined in 10 families with one or more children with JDM. A statistically significant association was found between HLA-D-identity and the chance to present JDM within a sibship. No such association was detectable with the SD antigens. A highly significant increase in the frequency of intra-HLA recombination was also found in these families.

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References

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