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. 1976 Mar;65(3):431-2.
doi: 10.1002/jps.2600650330.

Fluorometric assay of verapamil in biological fluids and tissues

R G McAllister, S M Howell

Fluorometric assay of verapamil in biological fluids and tissues

R G McAllister et al. J Pharm Sci. 1976 Mar.

Abstract

Verapamil concentrations in blood, urinee, or tissue homogenates may be measured fluorometrically in the 0.1-10-mug/ml range after extraction into heptane and back-extraction into acid; recovery rates are above 87%. The drug apparently is eliminated rapidly in guinea pigs, with a plasma half-life of 45 min.

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