Comment on

• Rapamycin inhibits primary and metastatic tumor growth by antiangiogenesis: involvement of vascular endothelial growth factor.

  Guba M, von Breitenbuch P, Steinbauer M, Koehl G, Flegel S, Hornung M, Bruns CJ, Zuelke C, Farkas S, Anthuber M, Jauch KW, Geissler EK. Guba M, et al. Nat Med. 2002 Feb;8(2):128-35. doi: 10.1038/nm0202-128. Nat Med. 2002. PMID: 11821896
• Rapamycin is an effective inhibitor of human renal cancer metastasis.

  Luan FL, Ding R, Sharma VK, Chon WJ, Lagman M, Suthanthiran M. Luan FL, et al. Kidney Int. 2003 Mar;63(3):917-26. doi: 10.1046/j.1523-1755.2003.00805.x. Kidney Int. 2003. PMID: 12631072