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Case Reports
. 2003 Jan;70(1):64-6.

Unstable angina associated with coronary arterial calcification in a thalassemia intermedia patient with a pseudoxanthoma elasticum-like syndrome

Dimitrios Farmakis  1 , Ioannis Moyssakis, Alexandros Perakis, Yiannis Rombos, Spyros Deftereos, Anastasios Giakoumis, Evangelos Polymeropoulos, Athanasios Aessopos
Affiliations
  • PMID: 12631261
Case Reports

Unstable angina associated with coronary arterial calcification in a thalassemia intermedia patient with a pseudoxanthoma elasticum-like syndrome

Dimitrios Farmakis et al. Eur J Haematol. 2003 Jan.

Abstract

The coexistence of a pseudoxanthoma elasticum (PXE)-like syndrome in beta-thalassemia and other hemoglobinopathies is a recently established clinical entity that has been observed with a significant frequency and related to some severe, even life-threatening complications. We present here a thalassemia intermedia patient who developed unstable angina in a setting of severe anemia and PXE-related coronary arterial calcification. Besides the clinical significance of this PXE-like syndrome, its acquired nature may introduce some new thoughts regarding the pathogenesis of atherosclerosis.

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