Prevention of coronary heart disease. Report of a Joint Working Party of the Royal College of Physicians of London and the British Cardiac Society
- PMID: 1263163
- PMCID: PMC5366397
Prevention of coronary heart disease. Report of a Joint Working Party of the Royal College of Physicians of London and the British Cardiac Society
Abstract
PIP: Factors in the prevention of coronary heart disease (CHD) are review ed. In regards to oral contraceptives (OCs), there is some evidence that OCs significantly increase the risk of CHD in women over 40 years of age who are already at increased risk. There have also been reports that the risk of developing myocardial infarction or coronary death is 5-6 times higher in women aged 40-44 years using OCs than in nonusers. OCs can induce hypertension, though this condition is generally reversible after discontinuation of use. There also appears to be a relationship between OC use and carotid or cerebrovascular thromboses. It is recommended that caution be exercised in prescribing OCs to women over 40 years of age, those with a family history of premature CHD, and those who are heavy cigarette smokers or have other risk factors. It is also recommended that prospective OC users have their blood pressure tak en, and those with a family history of CHD or diabetes mellitus should be tested for plasma lipid levels.
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