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. 1976 Mar 15;54(6):261-5.
doi: 10.1007/BF01468921.

[The effect of clonidine on renin-release (author's transl)]

[Article in German]
K A Meurer, G Kloos, A Helber, W Kaufmann

[The effect of clonidine on renin-release (author's transl)]

[Article in German]
K A Meurer et al. Klin Wochenschr. .

Abstract

In patients with primary hypertension, intravenous administration of 150 mug Clonidin caused a decrease in arterial pressure, renin activity, RPF, GFR and electrolyte excretion. Activation of intracerebral adrenergic alpha-receptors and diminished sympathetic outflow seem to be responsible for the decrease of renin release.

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