Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2003 Mar;24(3):519-22.

CT and MR imaging of intracerebral amyloidoma: case report and review of the literature

Dheeraj Gandhi  1 , Roberto Wee, Mayank Goyal
Affiliations
Review

CT and MR imaging of intracerebral amyloidoma: case report and review of the literature

Dheeraj Gandhi et al. AJNR Am J Neuroradiol. 2003 Mar.

Abstract

Intracerebral amyloidoma is the least common form of amyloid deposition in the brain. CT and MR imaging features in a case of pathologically proved cerebral amyloidoma are presented, and the available literature is reviewed. Typical imaging features of this entity include solitary or multiple supratentorial white matter masses that are hyperattenuated on nonenhanced CT. They have little or no mass effect on surrounding structures, extend medially up to the lateral ventricle wall, and have fine, irregular, enhancing margins.

PubMed Disclaimer

Figures

F<sc>ig</sc> 1.
Fig 1.
CT scans obtained in 54-year-old woman with intracerebral amyloidoma. A, Axial non-contrast enhanced CT scan of the brain reveals a hyperattenuated comet-shaped mass in the left posterior frontal white matter. Significant vasogenic edema is also present around the mass. B, The mass enhances after administration of contrast material. Note the medial extension of the mass up to the lateral ventricular ependyma.
F<sc>ig</sc> 2.
Fig 2.
MR images obtained in 54-year-old woman with intracerebral amyloidoma. A, The mass is hypointense on this axial T1-weighted image (551/5/2 [TR/TE/NEX]). B, The mass is hypointense on this axial T2-weighted image (4110/110/2). C, The mass is hyperintense on this T1-weighted postcontrast axial image.
See this image and copyright information in PMC

References

    1. Glenner GG. Amyloid deposits and amyloidosis. The β-fibrillosis. N Engl J Med 1980;302:1283–92, 1333–43 - PubMed
    1. Eriksson L, Sletten K, Benson L, Westermark P. Tumor-like localized amyloid of the brain is derived from immunoglobin light chain. Scand J Immunol 1993;37:623–626 - PubMed
    1. Lee J, Krol G, Rosenblum M. Primary amyloidoma of the brain: CT and MR presentation. AJNR Am J Neuroradiol 1995;16:712–714 - PMC - PubMed
    1. Caerts B, Mol V, Sainte T, Wilms G, Van Den Bergh V, Stessens L. CT and MRI of amyloidoma of the CNS. Eur Radiol 1997;7:474–476 - PubMed
    1. Salytkov S. Zur Frage des lokalen Amyloids des Hirengefabe. Bemerkung Zu dem Aufsatz von morgenstern Virchows Arch [A] 1935;295:590

MeSH terms