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. 1976 Feb 27;144(1):75-81.

Extrachromosomal inheritance in Schizosaccharomyces pombe. II. Evidence for extrakaryotically inherited respiratory deficient mutants

K Wolf, B Lang, G Burger, F Kaudewitz
  • PMID: 1264064

Extrachromosomal inheritance in Schizosaccharomyces pombe. II. Evidence for extrakaryotically inherited respiratory deficient mutants

K Wolf et al. Mol Gen Genet. .

Abstract

In contrast to the wild-type, mutant [ANTr8] is able spontaneously to throw off stable respiratory deficient mutants. The frequency of these mutants is considerably enhanced by treatment with ethidium bromide (EB) or the azo-dye Janus green (JG). An unstable cell state with a petite-like phenotype is found in both mutant [ANTr8] and wild-type after EB-treatment. However, only in the mutant is this unstable cell state followed by the appearance of stable respiratory deficient (RD) mutants. Formation of microcolonies is observed both in [ANTr8] and wild-type. RD mutants were isolated after EB treatment. Three of them (mit-12, mit-25, and mit-30) were analyzed and mit-25 characterized in more detail.

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References

    1. Antonie Van Leeuwenhoek. 1964;30:1-9 - PubMed
    1. Proc Natl Acad Sci U S A. 1975 Jun;72(6):2054-7 - PubMed
    1. Biochem Biophys Res Commun. 1973 Nov 1;55(1):125-31 - PubMed
    1. Biochim Biophys Acta. 1973 Feb 12;301(1):71-104 - PubMed
    1. Biochimie. 1973;55(6):779-92 - PubMed

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