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. 2003 Mar;9(3):376-9.
doi: 10.3201/eid0903.020531.

Persistence of virus-reactive serum immunoglobulin m antibody in confirmed west nile virus encephalitis cases

John T Roehrig  1 , Denis Nash, Beth Maldin, Anne Labowitz, Denise A Martin, Robert S Lanciotti, Grant L Campbell
Affiliations

Persistence of virus-reactive serum immunoglobulin m antibody in confirmed west nile virus encephalitis cases

John T Roehrig et al. Emerg Infect Dis. 2003 Mar.

Abstract

Twenty-nine laboratory-confirmed West Nile virus (WNV encephalitis patients were bled serially so that WNV-reactive immunoglobulin (Ig) M activity could be determined. Of those patients bled, 7 (60%) of 12 had anti-WNV IgM at approximately 500 days after onset. Clinicians should be cautious when interpreting serologic results from early season WNV IgM-positive patients.

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Figures

Figure
Figure
Scatterplot of anti–West Nile virus immunoglobulin M positive-to-negative (P/N) values of individual serum specimens over time. Dotted line represents P/N=3.0 cut-off.
See this image and copyright information in PMC

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