Antiviral flavonoids from the root bark of Morus alba L
- PMID: 12648543
- DOI: 10.1016/s0031-9422(02)00753-7
Antiviral flavonoids from the root bark of Morus alba L
Abstract
A prenylated flavonoid, moralbanone, along with seven known compounds kuwanon S, mulberroside C, cyclomorusin, eudraflavone B hydroperoxide, oxydihydromorusin, leachianone G and alpha-acetyl-amyrin were isolated from the root bark of Morus alba L. Leachianone G showed potent antiviral activity (IC(50) = 1.6 microg/ml), whereas mulberroside C showed weak activity (IC(50) = 75.4 microg/ml) against herpes simplex type 1 virus (HSV-1). Their structures were elucidated by spectroscopic methods.
Copyright 2003 Elsevier Science Ltd.
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