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. 2003 Apr;62(8):1235-8.
doi: 10.1016/s0031-9422(02)00753-7.

Antiviral flavonoids from the root bark of Morus alba L

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Antiviral flavonoids from the root bark of Morus alba L

Jiang Du et al. Phytochemistry. 2003 Apr.

Abstract

A prenylated flavonoid, moralbanone, along with seven known compounds kuwanon S, mulberroside C, cyclomorusin, eudraflavone B hydroperoxide, oxydihydromorusin, leachianone G and alpha-acetyl-amyrin were isolated from the root bark of Morus alba L. Leachianone G showed potent antiviral activity (IC(50) = 1.6 microg/ml), whereas mulberroside C showed weak activity (IC(50) = 75.4 microg/ml) against herpes simplex type 1 virus (HSV-1). Their structures were elucidated by spectroscopic methods.

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