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. 1976 Mar;52(605):151-3.
doi: 10.1136/pgmj.52.605.151.

Effects of beta-adrenergic blockade and stimulation on airways in normal subjects

G W Bradley, A K Henderson, R J Mills

Effects of beta-adrenergic blockade and stimulation on airways in normal subjects

G W Bradley et al. Postgrad Med J. 1976 Mar.

Abstract

The effects of propranolol and salbutamol on conventional pulmonary function tests and closing volume have been studied in ten normal subjects. Propranolol and salbutamol had minor effects on measurements of airways resistance but had no effect on closing volume which is particularly sensitive to changes in peripheral airways. It was concluded that propranolol had negligible overall effect on central and peripheral airways properties in normal subjects, and it would appear that β-adrenergic activity has little measurable influence on peripheral airways in normal man at rest.

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