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Clinical Trial
. 2003;55(1):45-7.
doi: 10.4081/reumatismo.2003.45.

[Safety of lornoxicam in G-6-PDH deficiency]

[Article in Italian]
G Perpignano  1 , E Cacace, C Matulli, V Ruggiero
Affiliations
Clinical Trial

[Safety of lornoxicam in G-6-PDH deficiency]

[Article in Italian]
G Perpignano et al. Reumatismo. 2003.

Abstract

Objective: To assess the safety of lornoxicam in subjects with G-6-PDH deficiency.

Methods: Open controlled 2-week in vivo study on lornoxicam 8 mg bid in subjects with G-6-PDH deficiency suffering from rheumatic diseases.

Results: In 8 male patients with the Mediterranean form of G-6-PDH deficiency (mean age +/- SD, 54.3 years +/- 7.2) lornoxicam showed no influence on red blood cells (RBC) survival curve. The RBC half-life was the same before and after two weeks of treatment.

Conclusions: Lornoxicam caused no RBC damage and evidenced favourable safety in subjects with G-6-PDH deficiency, suffering from rheumatic diseases.

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