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. 2003;92(1):111-3.
doi: 10.1111/j.1651-2227.2003.tb00479.x.

Frequency of and risk factors for necrotizing enterocolitis in infants born before 33 weeks of gestation

M Hällström  1 , A M Koivisto, M Janas, O Tammela
Affiliations

Frequency of and risk factors for necrotizing enterocolitis in infants born before 33 weeks of gestation

M Hällström et al. Acta Paediatr. 2003.

Abstract

Aim: To investigate the frequency of and risk factors for necrotizing enterocolitis (NEC) among infants of <33 wk of gestation.

Methods: Prospective follow-up of 140 inpatients.

Results: 26 (18.6%) subjects developed NEC stage I-III and 12 (8.6%) severe NEC (stage II-III). Breast milk fortifier and duration of morphine infusion emerged as the statistically significant factors associated with NEC stage I-III, but only the latter had a significant association with severe NEC.

Conclusion: Future studies are needed to be established whether morphine is a causative factor in NEC.

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