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. 2003 Apr 2;125(13):3696-7.
doi: 10.1021/ja029783+.

Arrays of mobile tethered vesicles on supported lipid bilayers

Chiaki Yoshina-Ishii  1 , Steven G Boxer
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Arrays of mobile tethered vesicles on supported lipid bilayers

Chiaki Yoshina-Ishii et al. J Am Chem Soc. .

Abstract

We report a new system of laterally mobile, arrayed vesicles that are encoded with DNA to control tethering to fluid-supported phospholipid bilayers. The motion of individual fluorescently labeled vesicles, specifically bound, are easily visualized by fluorescence video microscopy and observed to collide reversibly on the surface. This system is an ideal model for studying interactions involving membranes, in particular integral membrane proteins.

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