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Review
. 2003 Apr 4;68(7):2529-39.
doi: 10.1021/jo020728t.

Discovering nature's diverse pathways to vitamin B12: a 35-year odyssey

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Review

Discovering nature's diverse pathways to vitamin B12: a 35-year odyssey

A Ian Scott. J Org Chem. .

Abstract

The chronology of the discoveries along the pathway of vitamin B(12) biosynthesis is reviewed from a personal perspective, including discussion of the most recent finding that two pathways to B(12) exist-one aerobic and one anaerobic-which differ mainly in the ring contraction mechanisms that convert porphyrin to corrin.

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