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. 2003 Mar;66(3):438-40.
doi: 10.1021/np020497l.

Three new cytotoxic sesterterpenes from a marine sponge Spongia sp

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Three new cytotoxic sesterterpenes from a marine sponge Spongia sp

Sachiko Tsukamoto et al. J Nat Prod. 2003 Mar.

Abstract

Three new sesterterpenes (1-3) were isolated from a marine sponge of the genus Spongia, and their structures were determined on the basis of spectroscopic analysis. The compounds 1-3 exhibited cytotoxicity against HeLa cells with IC(50) values of 19.5, 15.0, and 5.3 microg/mL, respectively.

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