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Comparative Study
. 2003 May;227(2):567-74.
doi: 10.1148/radiol.2272020903. Epub 2003 Mar 27.

Sickle cell disease: continuous arterial spin-labeling perfusion MR imaging in children

Kader K Oguz  1 , Xavier Golay, Francesca B Pizzini, Catherine A Freer, Nevada Winrow, Rebecca Ichord, James F Casella, Peter C M van Zijl, Elias R Melhem
Affiliations
Comparative Study

Sickle cell disease: continuous arterial spin-labeling perfusion MR imaging in children

Kader K Oguz et al. Radiology. 2003 May.

Abstract

Cerebral blood flow (CBF) was measured with continuous arterial spin-labeling perfusion magnetic resonance (MR) imaging in 14 children with sickle cell disease and seven control subjects. Mean CBF values were higher in patients (P <.005) than in control subjects in all cerebral artery territories. Three patients had decreased CBF in right anterior and middle cerebral artery territories compared with CBF on the left, and one patient had a profound decrease in CBF in all three territories in the right hemisphere. Baseline CBF was significantly decreased in territories seen as unaffected on conventional MR images and MR angiograms in four children with sickle cell disease.

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