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. 2003 Mar;11(3):571-5.
doi: 10.1016/s1097-2765(03)00108-4.

Kleisins: a superfamily of bacterial and eukaryotic SMC protein partners

Alexander Schleiffer  1 , Susanne Kaitna, Sebastian Maurer-Stroh, Michael Glotzer, Kim Nasmyth, Frank Eisenhaber
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Free article

Kleisins: a superfamily of bacterial and eukaryotic SMC protein partners

Alexander Schleiffer et al. Mol Cell. 2003 Mar.
Free article

Abstract

We describe a superfamily of eukaryotic and prokaryotic proteins (kleisins) that includes ScpA, Scc1, Rec8, and Barren. Scc1 interacts with SMC proteins through N- and C-terminal domains to form a ring-like structure. Since these are the only domains conserved among kleisins, we suggest that ring formation with SMC proteins may define this family.

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