[Pentylenetetrazole kindling induces caspase-3 activation in rat brain]
[Article in
Russian]
Affiliations
- PMID: 12669512
Item in Clipboard
[Pentylenetetrazole kindling induces caspase-3 activation in rat brain]
[Article in
Russian]
Zh Vyssh Nerv Deiat Im I P Pavlova.
2003 Jan-Feb.
Abstract
Pentylenetetrazole kindling (but not a single pentylenetetrazole injection) induced caspase-3 activation in the cerebral cortex, hippocampus, and cerebellum of rats as well as neurodegeneration in the hippocampus. The number of neurons in the CA3 subfield of the hippocampus decreased significantly, whereas no apoptotic nuclei could be detected. The results support a possible non-apoptotic involvement of caspase-3 in brain plasticity.
Similar articles
-
Pentylenetetrazole kindling induces neuronal cyclin B1 expression in rat hippocampus.Neurosci Lett. 2006 Jan 9;392(1-2):154-8. doi: 10.1016/j.neulet.2005.09.021. Epub 2005 Oct 18. Neurosci Lett. 2006. PMID: 16242239
-
[Active avoidance learning in rats and morphological changes in the hippocampus after pentylenetetrazole kindling].Zh Vyssh Nerv Deiat Im I P Pavlova. 2009 Mar-Apr;59(2):213-20. Zh Vyssh Nerv Deiat Im I P Pavlova. 2009. PMID: 19445390 Russian.
-
Pentylenetetrazole kindling induces activation of caspase-3 in the rat brain.Neurosci Behav Physiol. 2004 Jan;34(1):45-7. doi: 10.1023/b:neab.0000003246.26997.10. Neurosci Behav Physiol. 2004. PMID: 15109082 No abstract available.
-
[The hippocampus as the determinant structure generating epileptic activity during korazol kindling].Biull Eksp Biol Med. 1985 May;99(5):527-32. Biull Eksp Biol Med. 1985. PMID: 3924136 Russian.
-
CCK-8 prevents the development of kindling and regulates the GABA and NPY expression in the hippocampus of pentylenetetrazole (PTZ)-treated adult rats.Neuropharmacology. 2005 Apr;48(5):732-42. doi: 10.1016/j.neuropharm.2004.12.001. Neuropharmacology. 2005. PMID: 15814107
Cited by
-
Anticonvulsant and related neuropharmacological effects of the whole plant extract of Synedrella nodiflora (L.) Gaertn (Asteraceae).J Pharm Bioallied Sci. 2012 Apr;4(2):140-8. doi: 10.4103/0975-7406.94816. J Pharm Bioallied Sci. 2012. PMID: 22557925 Free PMC article.
-
Acquisition of an active avoidance reaction in rats and morphological changes in the hippocampus in pentylenetetrazol kindling.Neurosci Behav Physiol. 2010 Jun;40(5):501-6. doi: 10.1007/s11055-010-9288-2. Epub 2010 May 14. Neurosci Behav Physiol. 2010. PMID: 20464515
-
Electroconvulsive shock induces neuron death in the mouse hippocampus: correlation of neurodegeneration with convulsive activity.Neurosci Behav Physiol. 2005 Sep;35(7):715-21. doi: 10.1007/s11055-005-0115-0. Neurosci Behav Physiol. 2005. PMID: 16433067
Publication types
MeSH terms
Substances
LinkOut - more resources
Research Materials
Miscellaneous