Bridging the synthetic and biopolymer worlds with peptide-drug conjugates
- PMID: 12670531
- DOI: 10.1016/s1074-5521(03)00056-5
Bridging the synthetic and biopolymer worlds with peptide-drug conjugates
Abstract
Roberts and Li break the standard library mold by generating hybrid libraries of small molecules tethered to peptides. Hybrid libraries harness larger chemical and structural diversities and thus represent a new frontier in lead drug discovery.
Comment on
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A novel strategy for in vitro selection of peptide-drug conjugates.Chem Biol. 2003 Mar;10(3):233-9. doi: 10.1016/s1074-5521(03)00047-4. Chem Biol. 2003. PMID: 12670537
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