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Review
. 2003 Apr;11(4):207-25.
doi: 10.1007/s00520-002-0407-7. Epub 2002 Nov 23.

Xerostomia and hypofunction of the salivary glands in cancer therapy

Siri Beier Jensen  1 , Anne Marie Pedersen, Jesper Reibel, Birgitte Nauntofte
Affiliations
Review

Xerostomia and hypofunction of the salivary glands in cancer therapy

Siri Beier Jensen et al. Support Care Cancer. 2003 Apr.

Abstract

This review presents data from the literature on oral adverse reactions from the perspectives of subjective feelings of dry mouth (xerostomia) and objective measures of salivary gland hypofunction during and after cancer therapy. Special emphasis is paid to the mechanisms behind xerostomia, impaired saliva secretion and changes in the composition of saliva and to how these relate to radiation therapy involving the salivary glands and to systemic chemotherapy. The oral complications that relate to such iatrogenic changes in salivary gland function are also discussed.

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Comment in

  • Xerostomia--any progress?
    Peterson DE. Peterson DE. Support Care Cancer. 2003 Apr;11(4):199-200. doi: 10.1007/s00520-003-0456-6. Epub 2003 Mar 12. Support Care Cancer. 2003. PMID: 12673457 Review. No abstract available.

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