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. 1976 Apr;9(4):587-8.
doi: 10.1128/AAC.9.4.587.

Effect of cephalothin on renal cortical concentrations of gentamicin in rats

P Dellinger, T Murphy, M Barza, V Pinn, L Weinstein

Effect of cephalothin on renal cortical concentrations of gentamicin in rats

P Dellinger et al. Antimicrob Agents Chemother. 1976 Apr.

Abstract

Renal cortical concentrations of gentamicin were significantly lower in rats given this aminoglycoside and cephalothin simultaneously than in animals given gentamicin alone. This effect may be responsible, in part, for the reduction in nephrotoxicity reported previously in animals given the combination of drugs.

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References

    1. J Infect Dis. 1975 Aug;132(2):165-74 - PubMed
    1. Antimicrob Agents Chemother. 1975 Aug;8(2):209-15 - PubMed
    1. Antimicrob Agents Chemother. 1976 Jan;9(1):172-8 - PubMed
    1. J Infect Dis. 1974 Dec;130(6):656-9 - PubMed
    1. Kidney Int. 1974 Sep;6(3):131-7 - PubMed

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