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. 1976 Jan;219(1):1-12.

Possible role of histamine receptors in cardiovascular responses to 5-hydroxytryptamine in the chicken

N Chand, P Eyre
  • PMID: 1267533

Possible role of histamine receptors in cardiovascular responses to 5-hydroxytryptamine in the chicken

N Chand et al. Arch Int Pharmacodyn Ther. 1976 Jan.

Abstract

Mepyramine (a selective H1-histamine receptor antagonist) and burimamide (a selective H2-receptor antagonist) specifically and equally modify the systemic hypotensive responses to both serotonin and histamine. Results suggest that both H1- and H2-histamine receptors in part mediate systemic arterial depressor and venous pressor responses to 5-HT in the domestic chicken.

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