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Review
. 2003 May;47(5):421-37.
doi: 10.1016/s1043-6618(03)00051-3.

Sphingolipids and the immune system

Benedetta Cinque  1 , Luisa Di Marzio, Carla Centi, Cristiana Di Rocco, Carlo Riccardi, M Grazia Cifone
Affiliations
Review

Sphingolipids and the immune system

Benedetta Cinque et al. Pharmacol Res. 2003 May.

Abstract

The importance of sphingolipids, not only as components of plasma membranes but also as key players in different physiological and pathophysiological cellular events, is now emerging. This review gathers together what the authors feel are the most relevant data, present in the literature, regarding the roles and the effects of sphingolipids, such as ceramide, ceramide-1-phosphate (C1P), sphingosine (SP) and sphingosine-1-phosphate (S1P), on the development, activation and regulation of the immune system.

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