Multifocal electroretinography in central serous chorio-retinopathy and assessment of the reproducibility of the multifocal electroretinography

Abstract

Purpose: To measure and compare the difference of multifocal electroretinography (mERG) in control subjects and patients with central serous chorio-retinopathy (CSCR) and assessing the reproducibility of the multifocal electroretinography.

Methods: Sixteen cases of control subjects and 12 cases of central serous chorio-retinopathy were tested with the Visual Evoked Response Imaging System science4.2 made by EDI company of America. The results of the left eye of each control subject and patient were used for statistical evaluation by the Mann-Whitney U test. Repeat measurements were performed on 11 control subjects. Wilcoxon technique were used to quantify the reproducibility of the test.

Results: The P1 waveform average response density of 1-3 rings in central serous chorio-retinopathy were decreased statistically. There was no significant difference between repeat measurements on 11 individuals.

Conclusion: Multifocal electroretinography can be used to quantify the visual function of the affected area in chorio-retinopathy and showed good agreement in the data distribution for the repeat measurements.