Review
doi: 10.2174/0929867033457386.
Cationic transfection lipids
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- PMID: 12678802
- DOI: 10.2174/0929867033457386
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Review
Cationic transfection lipids
Curr Med Chem.
2003 Jul.
Abstract
This review focuses on the recent developments in study of cationic lipids as carriers for DNA delivery. Emphasis is placed on a class of compounds as exemplifies by their similarity in structures and transfection activities. The technical aspects are also reviewed on how to prepare DNA-lipid complexes and to perform transfection. A brief discussion of the current views on the mechanism of cationic lipid-mediated DNA transfer is intended to provide new prospects for future developments and further improvement of the current systems.
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