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. 2003 May;34(1):32-3.
doi: 10.1038/ng1141.

Dax1 is required for testis determination

Joshua J Meeks  1 , Jeffrey Weiss, J Larry Jameson
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Dax1 is required for testis determination

Joshua J Meeks et al. Nat Genet. 2003 May.

Abstract

The orphan nuclear receptor, Dax1, was originally proposed to act as an 'anti-testis' factor. We find, however, that Nr0b1 (also called Dax1 and Ahch, which encodes Dax1) is in fact required for testis differentiation.

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