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Case Reports
. 2003 Apr;22(4):487-91.
doi: 10.1016/s1053-2498(02)00817-3.

Reactive hemophagocytic syndrome associated with disseminated histoplasmosis in a heart transplant recipient

Kalil Masri  1 , Niall Mahon, Adriana Rosario, Imran Mirza, Thomas F Keys, Norman B Ratliff, Randall C Starling
Affiliations
Case Reports

Reactive hemophagocytic syndrome associated with disseminated histoplasmosis in a heart transplant recipient

Kalil Masri et al. J Heart Lung Transplant. 2003 Apr.

Abstract

We describe a patient who developed multi-organ failure with reactive hemophagocytic syndrome secondary to disseminated histoplasmosis 8 months after orthotopic heart transplantation. The patient responded fully to a prolonged course of therapy with amphotericin B and remains free of recurrence. Disseminated histoplasmosis and reactive hemophagocytic syndrome have rarely been described in the setting of cardiac transplantation and never before in combination.

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