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. 2003 Apr;41(4):1772-4.
doi: 10.1128/JCM.41.4.1772-1774.2003.

Prenatal diagnosis of congenital human cytomegalovirus infection in amniotic fluid by nucleic acid sequence-based amplification assay

M Grazia Revello  1 , Daniele Lilleri, Maurizio Zavattoni, Milena Furione, Jaap Middeldorp, Giuseppe Gerna
Affiliations

Prenatal diagnosis of congenital human cytomegalovirus infection in amniotic fluid by nucleic acid sequence-based amplification assay

M Grazia Revello et al. J Clin Microbiol. 2003 Apr.

Abstract

Nucleic acid sequence-based amplification assays for detection of human cytomegalovirus (HCMV) immediate-early and pp67 mRNA in 65 amniotic fluid samples tested for prenatal diagnosis of congenital HCMV infection showed sensitivity, specificity, and negative and positive predictive values >90%.

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