Molecular therapeutics: is one promiscuous drug against multiple targets better than combinations of molecule-specific drugs?
- PMID: 12684387
Molecular therapeutics: is one promiscuous drug against multiple targets better than combinations of molecule-specific drugs?
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Antitumor effects of ZD6474, a small molecule vascular endothelial growth factor receptor tyrosine kinase inhibitor, with additional activity against epidermal growth factor receptor tyrosine kinase.Clin Cancer Res. 2003 Apr;9(4):1546-56. Clin Cancer Res. 2003. PMID: 12684431
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Combination of a selective cyclooxygenase-2 inhibitor with epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 and protein kinase A antisense causes cooperative antitumor and antiangiogenic effect.Clin Cancer Res. 2003 Apr;9(4):1566-72. Clin Cancer Res. 2003. PMID: 12684433
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