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Review
. 2003 Apr;4(4):442-4.
doi: 10.1016/s1534-5807(03)00100-x.

All roads lead to ATF4

D Thomas Rutkowski  1 , Randal J Kaufman
Affiliations
Free article
Review

All roads lead to ATF4

D Thomas Rutkowski et al. Dev Cell. 2003 Apr.
Free article

Abstract

Multiple intracellular stress pathways converge on a single event--phosphorylation of the translation initiation factor eIF2alpha and subsequent translational activation of the transcription factor ATF4. Exploring the consequences of this event has highlighted the ways in which stress is sensed and responded to via many distinct pathways.

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