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Case Reports
. 2003 Apr;105(2):102-4.
doi: 10.1016/s0303-8467(02)00125-7.

Central nervous system involvement in autoimmune polyglandular syndrome

Cavit Boz  1 , Sibel Velioglu, Vildan Altunayoğlu, Mehmet Ozmenoglu, Changir Erem
Affiliations
Case Reports

Central nervous system involvement in autoimmune polyglandular syndrome

Cavit Boz et al. Clin Neurol Neurosurg. 2003 Apr.

Abstract

We present a 33 year-old man, admitted because of transient deterioration of visual acuity. Magnetic resonance imaging showed diffuse central nervous system (CNS) demyelination, which largely resolved spontaneously within 4 months. The patient fulfilled the diagnostic criteria of APS type III, having autoimmune thyroiditis and alopecia universalis. In this patient, autoimmune activation against CNS antigens is thought to be the cause of reversible CNS demyelination.

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