doi: 10.1007/BF01937772.
The action of substance P on mesencephalic reticular and substantia nigral neurones of the rat
- PMID: 1269616
- DOI: 10.1007/BF01937772
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The action of substance P on mesencephalic reticular and substantia nigral neurones of the rat
Experientia.
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Abstract
Extracellular recordings were made from neurones in the mesencephalic reticular formation and substantianigra of the rat which was anaesthetized with urethane 1.5-2 g/kg i.p. Out of 44 cells tested 42 were excited by Substance P applied iontophoretically and in some cases this excitation was rapid. Evidence is presented for Substance P as a putative excitatory transmitter onto reticular and nigral neurones possibly released from primary sensory afferents.
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