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. 2002;98(2-3):206-9.
doi: 10.1159/000069809.

Molecular characterization of the porcine gene CAPNS1 encoding the small subunit 1 of calpain on SSC6q1.1-->q1.2

C Drögemüller  1 , T Leeb
Affiliations

Molecular characterization of the porcine gene CAPNS1 encoding the small subunit 1 of calpain on SSC6q1.1-->q1.2

C Drögemüller et al. Cytogenet Genome Res. 2002.

Abstract

The CAPNS1 gene encodes the small subunit of the calpain proteases. Cloning and characterization of the porcine CAPNS1 gene revealed a highly conserved organization with respect to other mammalian CAPNS1 orthologs. The porcine gene consists of 11 exons spanning approximately 7.3 kb and codes for a peptide of 266 amino acids. Analysis of the naturally occurring variation of the CAPNS1 gene in different pig breeds revealed six SNPs and four small insertion/deletion polymorphisms. The CAPNS1 gene is located immediately adjacent to the COX7A1 gene on SSC6q1.1-->q1.2.

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