[Correction of immune disorders with neoselenium in patients with chronic bronchitis]

Abstract

The examination covered 55 patients with chronic bronchitis (mean age 58 +/- 4.2 years, mean duration of the disease 11.2 +/- 5.2 years). All the patients were in remission and received broncholytics. In 32 of them, basic treatment was combined with a course of immunorehabilitation with neoselenium. The effect of the latter was assessed at immunological examination of the patients before and after the treatment with indirect immunofluorescence with monoclonal antibodies. Neoselenium appeared to have an immunomodulating action on all immunity links, it enhanced functional activity and bactericidity of antigen-presenting cells and cytotoxic activity of natural killers, diminished the tension in the function of endogenic antioxidant systems.