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Review
. 2003 Apr 15;53(8):691-700.
doi: 10.1016/s0006-3223(03)00087-8.

Acceleration and augmentation strategies for treating bipolar depression

Lori L Altshuler  1 , Mark A Frye, Michael J Gitlin
Affiliations
Review

Acceleration and augmentation strategies for treating bipolar depression

Lori L Altshuler et al. Biol Psychiatry. .

Abstract

Despite the prevalence and morbidity of bipolar depression, few randomized treatment trials have been conducted to assess clinical efficacy. Even fewer studies have assessed approaches that optimize treatment response for bipolar depression. This review will define three types of common combination strategies--adjunctive, acceleration and augmentation--and discuss the limited literature of controlled studies reported on acceleration and augmentation approaches.

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Comment in

  • "Difficult-to-treat depression".
    Kupfer DJ, Charney DS. Kupfer DJ, et al. Biol Psychiatry. 2003 Apr 15;53(8):633-4. doi: 10.1016/s0006-3223(03)00188-4. Biol Psychiatry. 2003. PMID: 12706948 No abstract available.

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