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. 2003 Apr 22;60(8):1344-7.
doi: 10.1212/01.wnl.0000065885.15875.0d.

Evaluation of essential tremor with multi-voxel magnetic resonance spectroscopy

Fernando L Pagan  1 , John A Butman, James M Dambrosia, Mark Hallett
Affiliations

Evaluation of essential tremor with multi-voxel magnetic resonance spectroscopy

Fernando L Pagan et al. Neurology. .

Abstract

The pathologic substrate of essential tremor (ET) remains unknown. The authors studied 10 patients with ET and 10 volunteers using a multislice MR spectroscopy imaging sequence. Left and right cerebellar hemisphere NAA/CR and NAA/Cho ratios were significantly smaller in the ET patients than healthy subjects. The authors' data suggest that the decreased NAA/Cr and NAA/Cho ratios within the cerebellum may represent an abnormality in neuronal function.

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