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. 1976 May;116(5):1415-8.

Isolation and partial characterization of SAA-an amyloid-related protein from human serum

C J Rosenthal, E C Franklin, B Frangione, J Greenspan
  • PMID: 1270801

Isolation and partial characterization of SAA-an amyloid-related protein from human serum

C J Rosenthal et al. J Immunol. 1976 May.

Abstract

A 12,000 dalton serum amyloid A protein (SAA) has been isolated by chromatography on Sephadex in 10% formic acid. It is similar immunologically to the previously characterized 8500 dalton tissue amyloid A (AA) protein. The results of amino acid analyses, peptide maps, and the identity of the first 11 residues of the SAA and AA proteins support the idea that AA represents the amino terminal fragment of SAA and is derived from it by proteolysis.

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