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. 2003 Feb;33(1):93-7.
doi: 10.1023/a:1022238706604.

Plasma amino acid levels in children with autism and their families

Sarah Aldred  1 , Kieran M Moore, Michael Fitzgerald, Rosemary H Waring
Affiliations

Plasma amino acid levels in children with autism and their families

Sarah Aldred et al. J Autism Dev Disord. 2003 Feb.

Abstract

Plasma amino acid levels were measured in autistic and Asperger syndrome patients, their siblings, and parents. The results were compared with values from age-matched controls. Patients with autism or Asperger syndrome and their siblings and parents all had raised glutamic acid, phenylalanine, asparagine, tyrosine, alanine, and lysine (p < .05) than controls, with reduced plasma glutamine. Other amino acids were at normal levels. These results show that children with autistic spectrum disorders come from a family background of dysregulated amino acid metabolism and provide further evidence for an underlying biochemical basis for the condition.

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