Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1976 Apr;118(4):193-9.
doi: 10.1002/path.1711180402.

The influence of enrichment with cholesterol on the phagocytic activity of rat macrophages

M U Dianzani, M V Torrielli, R A Canuto, R Garcea, F Feo

The influence of enrichment with cholesterol on the phagocytic activity of rat macrophages

M U Dianzani et al. J Pathol. 1976 Apr.

Abstract

Prolonged treatment of rats with a cholesterol-rich diet induced hypercholesterolaemia and increased free cholesterol content of peritoneal macrophages. A 2-2 times increase in plasma membrane cholesterol was demonstrated in cholesterol-enriched macrophages. These cells showed a significant inhibition of phagocytosis. The inhibition was 37-0% and 81-7% for latex particles or lipid droplets, respectively.

PubMed Disclaimer

MeSH terms

LinkOut - more resources