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. 2003 May 1;36(9):1197.
doi: 10.1086/374558. Epub 2003 Apr 21.

Serotonin syndrome after concomitant treatment with linezolid and citalopram

L Bernard  1 , R Stern, D Lew, P Hoffmeyer
Affiliations

Serotonin syndrome after concomitant treatment with linezolid and citalopram

L Bernard et al. Clin Infect Dis. .

Abstract

Linezolid, a new synthetic antimicrobial, is an important weapon against methicillin-resistant Staphylococcus aureus (MRSA). Although there are reports of serotonin syndrome developing after concomitant use of linezolid and the selective serotonin reuptake inhibitor paroxitene, this report concerns a patient receiving citalopram who developed thrombocytopenia, serotonin syndrome, and lactic acidosis and died following long-term linezolid therapy.

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Comment in

  • Linezolid and serotonin toxicity.
    Gillman PK. Gillman PK. Clin Infect Dis. 2003 Nov 1;37(9):1274-5. doi: 10.1086/378895. Clin Infect Dis. 2003. PMID: 14557977 No abstract available.

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